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The Cholesterol Transporter ABCA1 and Cholesterol Accumulation are Key Regulators of Adipose Function in Obesity

Cuffe, Helen Ann (Wake Forest University, 2015)

Obesity now affects over 1/3 of the U.S. adult population, and this number is predicted to grow in the next decades. In addition, obesity, and it’s related comorbidities, cost the U.S. healthcare system roughly $150 billion ...
RARE ABCA1 VARIANTS FOUND ONLY IN AFRICAN AMERICANS AND HOW THEY AFFECT LIPID EFFLUX AND NASCENT HDL FORMATION

Martinez, John (Wake Forest University, 2017)

Discovery of Tangier disease and subsequent discovery of ATP binding cassette transporter A1 (ABCA1) as the gene responsible for the disease has changed the study of lipoproteins due to almost non-existent levels of HDL-C ...
tissue-specific role of ATP binding cassette transporter A1 in atherogenesis

BI, XIN (Wake Forest University, 2013)

ATP binding cassette transporter A1 (ABCA1) facilitates cellular free cholesterol and phospholipid efflux across the plasma membrane to combine with apolipoproteins, forming nascent high density lipoproteins (HDL), the ...

Now showing items 1-3 of 3

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