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Browsing by Author "Vasquez-Valdivieso, Montserrat Guadalupe"

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Browsing by Author "Vasquez-Valdivieso, Montserrat Guadalupe"

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  • CHARACTERIZATION OF THE RNA BINDING MODE OF A PLATINUM-ACRIDINE AGENT 
    Vasquez-Valdivieso, Montserrat Guadalupe (Wake Forest University, 2009-08-18)
    Pt-ACRAMTU (ACRAMTU = 1-[2-(acridin-9-ylamino)ethyl]-1,3-dimethylthiourea) is a DNA-targeted anticancer agent that shows activity in a broad range of solid tumor cell lines. Unlike the classical platinum-based cross-linking ...