An Examination of the Function and the Transcriptional Regulation of the Bps Polysaccharide in Bordetella pertussis Pathogenesis and Biofilm Development
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- title
- An Examination of the Function and the Transcriptional Regulation of the Bps Polysaccharide in Bordetella pertussis Pathogenesis and Biofilm Development
- author
- Conover, Matthew Steven
- abstract
- Most bacterial species are capable of existing as surface-adhered communities encased in a matrix called biofilms. These aggregates of sessile bacteria are increasingly being associated with multiple human infections. However, the bacterial factors that contribute to biofilm formation are poorly understood. The identification of biofilm promoting factors and their control mechanisms are necessary for the efficient treatment of biofilm-mediated infections.
- subject
- attachment
- biofilm
- Bordetella
- nasal colonization
- polysaccharide regulation
- contributor
- Deora, Rajendar (committee chair)
- Mizel, Steve (committee member)
- Reid, Sean (committee member)
- Lively, Mark (committee member)
- date
- 2011-02-16T21:42:11Z (accessioned)
- 2012-12-10T09:30:06Z (available)
- 2010 (issued)
- degree
- Molecular Genetics & Genomics (discipline)
- embargo
- 2012-12-10 (terms)
- identifier
- http://hdl.handle.net/10339/30391 (uri)
- language
- en (iso)
- publisher
- Wake Forest University
- type
- Dissertation