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An Examination of the Function and the Transcriptional Regulation of the Bps Polysaccharide in Bordetella pertussis Pathogenesis and Biofilm Development

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abstract
Most bacterial species are capable of existing as surface-adhered communities encased in a matrix called biofilms. These aggregates of sessile bacteria are increasingly being associated with multiple human infections. However, the bacterial factors that contribute to biofilm formation are poorly understood. The identification of biofilm promoting factors and their control mechanisms are necessary for the efficient treatment of biofilm-mediated infections.
subject
attachment
biofilm
Bordetella
nasal colonization
polysaccharide regulation
contributor
Conover, Matthew Steven (author)
Deora, Rajendar (committee chair)
Mizel, Steve (committee member)
Reid, Sean (committee member)
Lively, Mark (committee member)
date
2011-02-16T21:42:11Z (accessioned)
2012-12-10T09:30:06Z (available)
2010 (issued)
degree
Molecular Genetics & Genomics (discipline)
embargo
2012-12-10 (terms)
identifier
http://hdl.handle.net/10339/30391 (uri)
language
en (iso)
publisher
Wake Forest University
title
An Examination of the Function and the Transcriptional Regulation of the Bps Polysaccharide in Bordetella pertussis Pathogenesis and Biofilm Development
type
Dissertation

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