ROLE OF 12/15 LIPOXYGENASE EXPRESSION IN LIPID METABOLISM, ATHEROSCLEROSIS AND INSULIN RESISTANCE
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Item Details
- title
- ROLE OF 12/15 LIPOXYGENASE EXPRESSION IN LIPID METABOLISM, ATHEROSCLEROSIS AND INSULIN RESISTANCE
- author
- Rong, Shunxing
- abstract
- 12/15 lipoxygenase (LO) is a member of a family of enzymes that can catalyze the stereospecific incorporation of oxygen into polyunsaturated fatty acids (PUFAs), forming a series of bioactive lipid mediators. Though lipid mediators produced by 12/15LO have the potential to affect lipid metabolism and atherosclerosis, the role of 12/15LO expression in these processes has not been elucidated.
- subject
- Atherosclerosis
- Lipid metabolism
- Lipoxygenase
- Macrophage
- contributor
- Parks, John S. (committee chair)
- Rudel, Lawrence L. (committee member)
- Temel, Ryan E. (committee member)
- Shelness, Gregory S. (committee member)
- date
- 2011-02-16T21:42:28Z (accessioned)
- 2011-06-10T08:30:11Z (available)
- 2010 (issued)
- degree
- Molecular Pathology (discipline)
- embargo
- 2011-06-10 (terms)
- identifier
- http://hdl.handle.net/10339/30414 (uri)
- language
- en (iso)
- publisher
- Wake Forest University
- type
- Dissertation