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A Novel Method to Assess Pulse Wave Velocity using Single Velocity Encoding in Phase Contrast Imaging

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abstract
The measurement of pulse wave velocity (PWV) using conventional phase contrast magnetic resonance imaging (PC-MRI) is recognized as a standard technique to assess arterial stiffness by measuring the arrival times of blood velocity waveforms. Conventional PC-MRI requires the acquisition of two sets of complex images with different velocity sensitivities or encodings. The two sets of phase images are then subtracted to yield a final quantitative velocity image independent of background phases, i.e. non flow related phase variations stemming from the magnetic field inhomogeneities. However, the acquisition of two sets of images represents a significant increase in scan time (or reduce in temporal resolution), thus limiting its application for PWV assessment.
subject
arterial stiffness
MRI
PC-MRI
phase contrast imaging
pulse wave velocity
contributor
Upreti, Asim (author)
Hamilton, Craig A (committee chair)
Santago, Peter (committee member)
Smith, Thomas L (committee member)
date
2011-07-14T20:35:38Z (accessioned)
2012-01-14T09:30:12Z (available)
2011 (issued)
degree
Biomedical Engineering (discipline)
embargo
2012-01-14 (terms)
identifier
http://hdl.handle.net/10339/33458 (uri)
language
en (iso)
publisher
Wake Forest University
title
A Novel Method to Assess Pulse Wave Velocity using Single Velocity Encoding in Phase Contrast Imaging
type
Thesis

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