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GENETIC VARIANTS OF ADIPOQ AND ASSOCIATION WITH PLASMA ADIPONECTIN LEVELS, TYPE 2 DIABETES, GLUCOSE HOMEOSTASIS AND ADIPOSITY

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abstract
Type 2 Diabetes is a complex disease characterized by a combination of environmental, lifestyle, and genetic factors. This study seeks to explore the genetic component of diabetes risk through evaluation of a candidate gene, ADIPOQ, encoding the adiponectin protein. Adiponectin is an adipocytokine that has been implicated in a wide variety of biomedical pathways, including glucose homeostasis and energy metabolism.
subject
adiponectin
adiposity
glucose homeostasis
proportion of variance
rare variants
type 2 diabetes
contributor
An, Si Sandy (author)
Bowden, Donald W (committee chair)
Ng, Maggie C (committee member)
Herrington, David M (committee member)
Antinozzi, Peter A (committee member)
Wang, Yuh-Hwa (committee member)
date
2012-06-12T08:35:55Z (accessioned)
2013-06-12T08:30:11Z (available)
2012 (issued)
degree
Biochemistry and Molecular Biology (discipline)
embargo
2013-06-12 (terms)
identifier
http://hdl.handle.net/10339/37273 (uri)
language
en (iso)
publisher
Wake Forest University
title
GENETIC VARIANTS OF ADIPOQ AND ASSOCIATION WITH PLASMA ADIPONECTIN LEVELS, TYPE 2 DIABETES, GLUCOSE HOMEOSTASIS AND ADIPOSITY
type
Dissertation

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