A Complete Dosimetric Model of the Gamma Knife Perfexion Using Penelope Monte Carlo Codes
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- title
- A Complete Dosimetric Model of the Gamma Knife Perfexion Using Penelope Monte Carlo Codes
- author
- Best, Ryan C. M.
- abstract
- The Gamma Knife Perfexion is a radiosurgical treatment device used to irradiate targets in the head. It uses 192 high-activity Cobalt-60 sources collimated to a common focus to impart radiological damage to the target structure while minimizing dose to adjacent healthy tissue. Tungsten collimators are organized into eight sectors of 24 sources each; each sector can be set to one of three collimation sizes. The collimators can produce nominal spheres of dose 16 mm, 8 mm, or 4 mm in diameter at the focus. Planning for Gamma Knife stereotactic radiosurgery (GK SRS) is performed using images from computed tomography (CT) and/or magnetic resonance (MR) imaging, as well as manual skull measurements. The manufacturer's software used to plan the delivery of these treatments uses a simplistic set of assumptions that do not consider heterogeneous tissue structures.
- subject
- dose distribution
- independent check
- Maximum Allowed Dose Difference
- radiosurgery
- stereotactic
- verification
- contributor
- Bourland, J. Daniel (committee chair)
- Hinson, William H (committee member)
- Holzwarth, George (committee member)
- Salsbury, Jr., Fred R (committee member)
- Munley, Michael T (committee member)
- date
- 2012-09-05T08:35:21Z (accessioned)
- 2013-03-05T09:30:05Z (available)
- 2012 (issued)
- degree
- Physics (discipline)
- embargo
- 2013-03-05 (terms)
- identifier
- http://hdl.handle.net/10339/37443 (uri)
- language
- en (iso)
- publisher
- Wake Forest University
- type
- Dissertation