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GENETIC ANALYSIS OF THE GLUCOCORTICOID PATHWAY IN THE SEVERE ASTHMA RESEARCH PROGRAM

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abstract
Asthma is a common lung disease affecting approximately 10% of the population in the United States. Approximately 10% of the individuals with asthma have a severe form of asthma that is inherently difficult to treat due to a poor response to treatment, namely inhaled corticosteroids (ICS). Understanding the molecular determinants that dictate steroid response would be a powerful tool in devising more effective treatment regiments for these individuals.
subject
Asthma
Genetics
Glucocorticoids
Pharmacogenetics
contributor
Robinson, Mac Breven (author)
Meyers, Deborah A (committee chair)
Hawkins, Gregory A (committee member)
Li, Xingnan (committee member)
date
2013-01-09T09:35:19Z (accessioned)
2012 (issued)
degree
Clinical and Population Translational Sciences (discipline)
10000-01-01 (liftdate)
embargo
forever (terms)
identifier
http://hdl.handle.net/10339/37671 (uri)
language
en (iso)
publisher
Wake Forest University
title
GENETIC ANALYSIS OF THE GLUCOCORTICOID PATHWAY IN THE SEVERE ASTHMA RESEARCH PROGRAM
type
Thesis

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