GENETIC ANALYSIS OF THE GLUCOCORTICOID PATHWAY IN THE SEVERE ASTHMA RESEARCH PROGRAM
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- abstract
- Asthma is a common lung disease affecting approximately 10% of the population in the United States. Approximately 10% of the individuals with asthma have a severe form of asthma that is inherently difficult to treat due to a poor response to treatment, namely inhaled corticosteroids (ICS). Understanding the molecular determinants that dictate steroid response would be a powerful tool in devising more effective treatment regiments for these individuals.
- subject
- Asthma
- Genetics
- Glucocorticoids
- Pharmacogenetics
- contributor
- Meyers, Deborah A (committee chair)
- Hawkins, Gregory A (committee member)
- Li, Xingnan (committee member)
- date
- 2013-01-09T09:35:19Z (accessioned)
- 2012 (issued)
- degree
- Clinical and Population Translational Sciences (discipline)
- 10000-01-01 (liftdate)
- embargo
- forever (terms)
- identifier
- http://hdl.handle.net/10339/37671 (uri)
- language
- en (iso)
- publisher
- Wake Forest University
- title
- GENETIC ANALYSIS OF THE GLUCOCORTICOID PATHWAY IN THE SEVERE ASTHMA RESEARCH PROGRAM
- type
- Thesis