Ethosuximide, a T-type Calcium Channel Antagonist, Reduces Alcohol Withdrawal Seizure
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- abstract
- Alcohol is the third highest risk factor for health related problems in the world and leads to over two million deaths per year. Individuals abusing alcohol frequently cycle between drinking and withdrawal states, which among other adverse side effects can induce withdrawal seizures. Alcohol withdrawal seizures are a major component of relapse and represent a significant barrier to recovery. Unfortunately, alcohol withdrawal seizures can cause more serious consequences such as status epilepticus and temporal lobe epilepsy, severe life-threatening conditions that often result in death.
- subject
- alcohol
- ethosuximide
- seizure
- T-type calcium channel
- withdrawal
- contributor
- Godwin, Dwayne W (committee chair)
- Salinas, Emilio (committee member)
- Jones, Sara (committee member)
- McCool, Brian (committee member)
- Weiner, Jeff (committee member)
- date
- 2014-07-10T08:35:43Z (accessioned)
- 2015-07-10T08:30:11Z (available)
- 2014 (issued)
- degree
- Neuroscience (discipline)
- embargo
- 2015-07-10 (terms)
- identifier
- http://hdl.handle.net/10339/39329 (uri)
- language
- en (iso)
- publisher
- Wake Forest University
- title
- Ethosuximide, a T-type Calcium Channel Antagonist, Reduces Alcohol Withdrawal Seizure
- type
- Dissertation