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Real-World and Population-Based Studies of Head Injury Causation

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abstract
Traumatic brain injury (TBI) is a major public health concern in the United States often resulting in long-term effects on quality of life and premature mortality. Previous experimental studies have identified TBI as an acceleration-based injury, often resulting from direct contact or loading to the head in combination with rotational forces. However, due to the complexity in loading conditions in injurious events, there is still much that is unknown about the mechanistic differences between different types of head injuries and how these injuries may be mitigated. Analysis of real-world data is beneficial in that it creates a research paradigm in which researchers are able to relate information about the biomechanical evidence, including the `insult' or mechanism, to the resulting injury. Focusing research on particular populations, ages, and/or genders allows for the development of population-specific injury metrics and prevention efforts.
subject
contributor
Urban, Jillian Elizabeth (author)
Stitzel, Joel D (committee chair)
Duma, Stefan (committee member)
Rowson, Steven (committee member)
Gayzik, Scott (committee member)
Maldjian, Joseph A (committee member)
Whitlow, Christopher T (committee member)
date
2015-06-23T08:35:35Z (accessioned)
2017-06-22T08:30:08Z (available)
2015 (issued)
degree
Biomedical Engineering (discipline)
embargo
2017-06-22 (terms)
identifier
http://hdl.handle.net/10339/57101 (uri)
language
en (iso)
publisher
Wake Forest University
title
Real-World and Population-Based Studies of Head Injury Causation
type
Dissertation

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