QUANTITATIVE DETECTION OF LIVER-RELEVANT BIOMARKERS BY SERS-IMMUNOLABALED GOLD NANOPARTICLES
Electronic Theses and Dissertations
Item Files
Item Details
- abstract
- Lab-on-a-chip technology has the potential to rapidly change the way experiments are conducted in a variety of fields ranging from medicine to environmental science. Specifically, sensors, detectors, and monitoring devices are increasingly being miniaturized to perform many experiments or measurements on a single chip. In this research, we develop an immunolabeled gold nanoparticle complex capable of detecting liver organoid biomarkers intended for use in a microfluidic device. Human Serum Albumin (HSA) and α-Glutathione S-Transferase (α-GST) are liver biomarkers that indicate liver health and damage respectively. Herein we demonstrate
- subject
- biosensing
- biosensor
- Gold nanoparticles
- lab-on-a-chip
- plasmonics
- contributor
- Mohs, Aaron M (committee chair)
- Levi, Nicole H (committee member)
- date
- 2015-08-25T08:35:28Z (accessioned)
- 2015-08-25T08:35:28Z (available)
- 2015 (issued)
- degree
- Biomedical Engineering (discipline)
- identifier
- http://hdl.handle.net/10339/57254 (uri)
- language
- en (iso)
- publisher
- Wake Forest University
- title
- QUANTITATIVE DETECTION OF LIVER-RELEVANT BIOMARKERS BY SERS-IMMUNOLABALED GOLD NANOPARTICLES
- type
- Thesis