Naturally Derived Scaffolds for Treatment of Volumetric Muscle Loss
Electronic Theses and Dissertations
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Item Details
- title
- Naturally Derived Scaffolds for Treatment of Volumetric Muscle Loss
- author
- Baker, Hannah Besser
- abstract
- Volumetric muscle loss (VML) is defined as the irrecoverable loss of function in skeletal muscle as a result of tissue loss. Herein, cell and growth factor loaded keratin hydrogels and Tissue Engineered Muscle Repair (TEMR) constructs consisting of cell seeded, cyclic stretched bladder acellular matrix (BAM), were investigated in VML injuries in which the overriding hypothesis was that these technologies would improve functional recovery and tissue morphology in otherwise irrecoverable injuries.
- subject
- Bladder Acellular Matrix
- Keratin
- Rodent Model
- Skeletal Muscle
- Tissue Engineering
- Volumetric Muscle Loss
- contributor
- Christ, George J. (committee chair)
- Almeida-Porada, Graca (committee member)
- Goldstein, Aaron (committee member)
- Grange, Robert (committee member)
- Kaplan, David (committee member)
- Mohs, Aaron (committee member)
- date
- 2015-08-25T08:35:30Z (accessioned)
- 2017-08-24T08:30:13Z (available)
- 2015 (issued)
- degree
- Biomedical Engineering (discipline)
- embargo
- 2017-08-24 (terms)
- identifier
- http://hdl.handle.net/10339/57256 (uri)
- language
- en (iso)
- publisher
- Wake Forest University
- type
- Dissertation