Item Details

title

EFFECTS OF BACLOFEN AND PHENMETRAZINE ON NEURONAL SIGNALING PATHWAYS IMPLICATED IN PSYCHOSTIMULANT ADDICTION

author

Keegan, Bradley Michael

abstract

Substance use disorders (SUDs) and addictions are serious mental conditions with profound consequences on both an individual and society. In the United States alone, the total estimated cost of substance abuse, including lost productivity-, crime-, and health- related costs, exceeds $700 billion per year (National Drug Intelligence Center, 2011); yet, funding for research through the National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism only amounts to $1.02 billion and $446 million of that cost, respectively, in Fiscal Year 2015 (“Justification of Estimates for Appropriations Committees: Fiscal Year 2015 ,” 2015). Meanwhile, in the face of substantial increases in federal funding for drug-prevention programs and law enforcement, addictive drugs continue to pose a growing threat to our national health.

subject

Addiction

Amphetamine

Baclofen

Cocaine

Phenmetrazine

Psychostimulant

contributor

Howlett, Allyn C (committee chair)

Chen, Rong (committee member)

Childers, Steven R (committee member)

date

2016-01-11T09:35:24Z (accessioned)

2017-01-10T09:30:13Z (available)

2015 (issued)

degree

Biomedical Science – MS (discipline)

embargo

2017-01-10 (terms)

identifier

http://hdl.handle.net/10339/57436 (uri)

language

en (iso)

publisher

Wake Forest University

type

Thesis