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THE THRIVE STUDY: FEASIBILITY AND PRELIMINARY EFFECTS OF A WEIGHT MAINTENANCE INTERVENTION FOR BREAST CANCER SURVIVORS UNDERGOING CHEMOTHERAPY

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abstract
PURPOSE: The purpose of the THRIVE study was to determine the feasibility of conducting a weight maintenance intervention for women with newly diagnosed stage I-IV breast cancer during chemotherapy. METHODS: Feasibility was determined by recruitment, accrual, adherence rates, perceived barriers, adverse events, and program satisfaction. RESULTS: Fifty-four women were eligible for the study. Twenty women agreed to participate (37%; age range 29-64 years (M=51, SD=10). With an accrual rate of approximately 1 participant per month, the target goal was met in 22 months. The adherence rate (testing visits and intervention sessions) was 95% with time constraint and distance the most often cited barriers to participation. There were no adverse events and participants reported an overall high program satisfaction (3.7 ± 0.6 out of 4 scale). In exploratory analyses, there were positive changes in self-reported days/week of moderate physical activity (p = .01) and accelerometer derived minutes/day of moderate-vigorous physical activity (p = .04), with no change in caloric intake or body composition from baseline to 6-months. CONCLUSION: The THRIVE intervention was feasible and preliminary data yielded useful results regarding weight maintenance in this patient population. Future studies are warranted to examine the impact of physical activity and nutrition programs on successful weight management during chemotherapy.
subject
Breast Cancer
Chemotherapy
Maintenance
Nutrition
Physical Activity
Weight
contributor
Oliver, Sarah Lynn (author)
Mihalko, Ph.D., Shannon L (committee chair)
Miller, Ph.D., Gary (committee member)
date
2016-05-21T08:35:54Z (accessioned)
2016 (issued)
degree
Health and Exercise Science (discipline)
2021-06-01 (liftdate)
embargo
2021-06-01 (terms)
identifier
http://hdl.handle.net/10339/59327 (uri)
language
en (iso)
publisher
Wake Forest University
title
THE THRIVE STUDY: FEASIBILITY AND PRELIMINARY EFFECTS OF A WEIGHT MAINTENANCE INTERVENTION FOR BREAST CANCER SURVIVORS UNDERGOING CHEMOTHERAPY
type
Thesis

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