Item Details

title

QUANTIFYING RADIATION INDUCED CORTICAL BONE LOSS USING COMPUTED TOMOGRAPHY (CT) IMAGING

author

Okoukoni, Catherine

abstract

Bone fracture is a major complication of radiation therapy (RT). The etiology of RT-induced fractures is unclear, but likely involves bone damage and deterioration. Unfortunately, there remains a paucity of quantitative data on structural bone changes after exposure to RT. The primary goal of this project is to quantify RT-related structural bone changes in cancer patients using computed tomography (CT) scans obtained in the course of treatment. Our hypothesis is that exposure to radiation produces early structural changes in the cortical and trabecular bone compartments.

subject

Bone

Computed Tomography

Radiation

Toxicity

contributor

Munley, Michael T (committee chair)

Willey, Jeffery S (committee member)

Blackstock, A. William (committee member)

Weaver, Ashley A (committee member)

Bourland, J.Daniel (committee member)

date

2017-06-15T08:35:29Z (accessioned)

2019-06-14T08:30:12Z (available)

2017 (issued)

degree

Biomedical Engineering (discipline)

embargo

2019-06-14 (terms)

identifier

http://hdl.handle.net/10339/82159 (uri)

language

en (iso)

publisher

Wake Forest University

type

Dissertation