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QUANTIFYING RADIATION INDUCED CORTICAL BONE LOSS USING COMPUTED TOMOGRAPHY (CT) IMAGING

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abstract
Bone fracture is a major complication of radiation therapy (RT). The etiology of RT-induced fractures is unclear, but likely involves bone damage and deterioration. Unfortunately, there remains a paucity of quantitative data on structural bone changes after exposure to RT. The primary goal of this project is to quantify RT-related structural bone changes in cancer patients using computed tomography (CT) scans obtained in the course of treatment. Our hypothesis is that exposure to radiation produces early structural changes in the cortical and trabecular bone compartments.
subject
Bone
Computed Tomography
Radiation
Toxicity
contributor
Okoukoni, Catherine (author)
Munley, Michael T (committee chair)
Willey, Jeffery S (committee member)
Blackstock, A. William (committee member)
Weaver, Ashley A (committee member)
Bourland, J.Daniel (committee member)
date
2017-06-15T08:35:29Z (accessioned)
2019-06-14T08:30:12Z (available)
2017 (issued)
degree
Biomedical Engineering (discipline)
embargo
2019-06-14 (terms)
identifier
http://hdl.handle.net/10339/82159 (uri)
language
en (iso)
publisher
Wake Forest University
title
QUANTIFYING RADIATION INDUCED CORTICAL BONE LOSS USING COMPUTED TOMOGRAPHY (CT) IMAGING
type
Dissertation

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