Genetic Sequencing in Healthy Populations
Electronic Theses and Dissertations
Item Files
Item Details
- abstract
- After the success of the Human Genome Project, genetic sequencing technology has improved exponentially. Consumers can now have parts of their genome sequenced for under $100. Genetic sequencing in this direct-to-consumer (DTC) setting comes with many ethical problems that, despite being brought to national attention almost ten years ago, still have not been addressed. Significant regulation is needed in DTC genetic sequencing. As genetic sequencing becomes more widely available, Whole Genome Sequencing (WGS) will move into the clinical space, providing massive amounts of information about patients. Many have suggested using this technology in the standard screening of healthy populations. This brings ethical dilemmas as well, particularly when considering the use of WGS in fetuses, infants, and children. While WGS may be acceptable for use in adults if adequate safeguards are put into place, parents have a moral duty, based on the child’s right to future autonomy and right not to know genetic information, not to permit WGS to be performed on their children.
- subject
- direct-to-consumer genetic testing
- ethics
- genetic screening
- genetic testing
- newborn screening
- whole genome sequencing
- contributor
- King, Nancy (committee chair)
- Hall, Mark (committee member)
- Coughlin, Christine (committee member)
- date
- 2018-05-24T08:35:46Z (accessioned)
- 2018-05-24T08:35:46Z (available)
- 2018 (issued)
- degree
- Bioethics (discipline)
- identifier
- http://hdl.handle.net/10339/90687 (uri)
- language
- en (iso)
- publisher
- Wake Forest University
- title
- Genetic Sequencing in Healthy Populations
- type
- Thesis