Item Details

title

Association of baseline sex hormone levels and prevalent and incident peripheral arterial disease in the Multi-Ethnic Study of Atherosclerosis

author

Goldman, Matthew Patrick

abstract

Peripheral arterial disease (PAD) is a progressive disease that affects up to 10% of the population worldwide. The burden of this disease on individuals, health systems, and communities remains high and will likely only increase as our population continues to age. While treatment and prevention paradigms for this disease are continuing to progress, new and novel therapies are being studied regularly. Increasingly, the role of endogenous and exogenous sex hormones (including estrogen and testosterone) in the development and treatment of cardiovascular diseases is being examined. In this thesis we evaluate the association between baseline endogenous sex hormone levels and peripheral arterial disease in a multi-ethnic population cohort from the Multi-Ethnic Study of Atherosclerosis (MESA).

subject

Cardiovascular Disease

Peripheral Vascular Disease

Sex Hormones

Testosterone

contributor

Edwards, Matthew S (committee chair)

Burke, Gregory L (committee member)

Case, Douglas (committee member)

Tooze, Janet (committee member)

date

2019-01-11T09:35:15Z (accessioned)

2019-01-11T09:35:15Z (available)

2018 (issued)

degree

Clinical and Population Translational Sciences (discipline)

identifier

http://hdl.handle.net/10339/93046 (uri)

language

en (iso)

publisher

Wake Forest University

type

Thesis