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Nonuniform Internal Structure of Fibrin Fibers: Protein Density and Bond Density Strongly Decrease with Increasing Diameter

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title
Nonuniform Internal Structure of Fibrin Fibers: Protein Density and Bond Density Strongly Decrease with Increasing Diameter
author
Li, W.
author
Sigley, J.
author
Baker, S.
author
Helms, C.
author
Kinney, M.
author
Pieters, M.
author
Brubaker, P.
author
Cubcciotti, R.
author
Guthold, M.
abstract
The major structural component of a blood clot is a meshwork of fibrin fibers. It has long been thought that the internal structure of fibrin fibers is homogeneous; that is, the protein density and the bond density between protofibrils are uniform and do not depend on fiber diameter. We performed experiments to investigate the internal structure of fibrin fibers.
subject
fibrin
date
2020-03-09T14:59:43Z (accessioned)
2020-03-09T14:59:43Z (available)
10/10/17 (issued)
identifier
Li, Wei, Justin Sigley, Stephen R. Baker, Christine C. Helms, Mary T. Kinney, Marlien Pieters, Peter H. Brubaker, Roger Cubcciotti, and Martin Guthold. "Nonuniform internal structure of fibrin fibers: protein density and bond density strongly decrease with increasing diameter." BioMed research international 2017 (2017). (citation)
http://hdl.handle.net/10339/96036 (uri)
identifier
https://doi.org/10.1155/2017/6385628 (doi)
language
en (iso)
publisher
Hindawi
rights
https://creativecommons.org/licenses/by/4.0/ (uri)
type
Article

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