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Nonuniform Internal Structure of Fibrin Fibers: Protein Density and Bond Density Strongly Decrease with Increasing Diameter

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abstract
The major structural component of a blood clot is a meshwork of fibrin fibers. It has long been thought that the internal structure of fibrin fibers is homogeneous; that is, the protein density and the bond density between protofibrils are uniform and do not depend on fiber diameter. We performed experiments to investigate the internal structure of fibrin fibers.
subject
fibrin
contributor
Li, W. (author)
Sigley, J. (author)
Baker, S. (author)
Helms, C. (author)
Kinney, M. (author)
Pieters, M. (author)
Brubaker, P. (author)
Cubcciotti, R. (author)
Guthold, M. (author)
date
2020-03-09T14:59:43Z (accessioned)
2020-03-09T14:59:43Z (available)
10/10/17 (issued)
identifier
Li, Wei, Justin Sigley, Stephen R. Baker, Christine C. Helms, Mary T. Kinney, Marlien Pieters, Peter H. Brubaker, Roger Cubcciotti, and Martin Guthold. "Nonuniform internal structure of fibrin fibers: protein density and bond density strongly decrease with increasing diameter." BioMed research international 2017 (2017). (citation)
https://doi.org/10.1155/2017/6385628 (doi)
http://hdl.handle.net/10339/96036 (uri)
language
en (iso)
publisher
Hindawi
rights
https://creativecommons.org/licenses/by/4.0/ (uri)
title
Nonuniform Internal Structure of Fibrin Fibers: Protein Density and Bond Density Strongly Decrease with Increasing Diameter
type
Article

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