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Nonuniform Internal Structure of Fibrin Fibers: Protein Density and Bond Density Strongly Decrease with Increasing Diameter

Open Access Fund Publications

abstract: The major structural component of a blood clot is a meshwork of fibrin fibers. It has long been thought that the internal structure of fibrin fibers is homogeneous; that is, the protein density and the bond density between protofibrils are uniform and do not depend on fiber diameter. We performed experiments to investigate the internal structure of fibrin fibers.
subject: fibrin
contributor: Li, W. (author); Sigley, J. (author); Baker, S. (author); Helms, C. (author); Kinney, M. (author); Pieters, M. (author); Brubaker, P. (author); Cubcciotti, R. (author); Guthold, M. (author)
date: 2020-03-09T14:59:43Z (accessioned); 2020-03-09T14:59:43Z (available); 10/10/17 (issued)
identifier: Li, Wei, Justin Sigley, Stephen R. Baker, Christine C. Helms, Mary T. Kinney, Marlien Pieters, Peter H. Brubaker, Roger Cubcciotti, and Martin Guthold. "Nonuniform internal structure of fibrin fibers: protein density and bond density strongly decrease with increasing diameter." BioMed research international 2017 (2017). (citation); https://doi.org/10.1155/2017/6385628 (doi); http://hdl.handle.net/10339/96036 (uri)
language: en (iso)
publisher: Hindawi
rights: https://creativecommons.org/licenses/by/4.0/ (uri)
title: Nonuniform Internal Structure of Fibrin Fibers: Protein Density and Bond Density Strongly Decrease with Increasing Diameter
type: Article