Item Details

title

EXPLORING GROUP DIFFERENCES IN WHITE MATTER HEALTH IN OLDER ADULT FALLERS AND NON-FALLERS WITH MCI

author

Taylor, Brandi Camille

abstract

Older individuals with MCI experience increased fall risk. However, the precise mechanism behind this increased fall risk remains unknown. Current literature suggests that increased fall risk may be the result of impaired balance and gait. Abnormalities in microstructural integrity of white matter may contribute to impaired balance and gait. This is the first study to utilize the NODDI technique to explore group differences in white matter health in older adult with MCI who were classified as fallers and non-fallers. Baseline data from 56 participants within the ongoing IMOVE study was used to explore group differences. NODDI derived NDI and ODI values were calculated from diffusion data from 39 participants.

subject

DTI

Fall

MCI

NODDI

contributor

Hugenschmidt, Christina E (committee chair)

Marsh, Anthony P (committee member)

Callahan, Kathryn E (committee member)

date

2020-05-29T08:36:11Z (accessioned)

2020-11-28T09:30:14Z (available)

2020 (issued)

degree

Neuroscience (discipline)

embargo

2020-11-28 (terms)

identifier

http://hdl.handle.net/10339/96852 (uri)

language

en (iso)

publisher

Wake Forest University

type

Thesis