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EXPLORING GROUP DIFFERENCES IN WHITE MATTER HEALTH IN OLDER ADULT FALLERS AND NON-FALLERS WITH MCI

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abstract
Older individuals with MCI experience increased fall risk. However, the precise mechanism behind this increased fall risk remains unknown. Current literature suggests that increased fall risk may be the result of impaired balance and gait. Abnormalities in microstructural integrity of white matter may contribute to impaired balance and gait. This is the first study to utilize the NODDI technique to explore group differences in white matter health in older adult with MCI who were classified as fallers and non-fallers. Baseline data from 56 participants within the ongoing IMOVE study was used to explore group differences. NODDI derived NDI and ODI values were calculated from diffusion data from 39 participants.
subject
DTI
Fall
MCI
NODDI
contributor
Taylor, Brandi Camille (author)
Hugenschmidt, Christina E (committee chair)
Marsh, Anthony P (committee member)
Callahan, Kathryn E (committee member)
date
2020-05-29T08:36:11Z (accessioned)
2020-11-28T09:30:14Z (available)
2020 (issued)
degree
Neuroscience (discipline)
embargo
2020-11-28 (terms)
identifier
http://hdl.handle.net/10339/96852 (uri)
language
en (iso)
publisher
Wake Forest University
title
EXPLORING GROUP DIFFERENCES IN WHITE MATTER HEALTH IN OLDER ADULT FALLERS AND NON-FALLERS WITH MCI
type
Thesis

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