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THE EFFECT OF SUBCONCUSSIVE IMPACTS ON THE INTERHEMISPHERIC CONNECTIVITY OF BRAIN REGIONS IMPLICATED IN DEPRESSION AND ANXIETY OF HIGH SCHOOL AND YOUTH FOOTBALL PLAYERS AFTER ONE FULL SEASON OF PLAY

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abstract
With millions of youth and high school football players worldwide, it is imperative that we understand how head impacts affect the developing brain. While much of the scientific literature focuses on impacts that result in concussions, the literature is lacking on subconcussive impacts. The focus of this study was to examine the effects of repetitive subconcussive head impacts on the interhemispheric connectivity for 20 regions of interest associated with depression and other mood disorders following a player’s first full year of football for 61 high school football players and 94 youth football players compared to respective controls (10 high schoolers and 18 youth). For youth players, there was a significant difference in the frontal region of the brain and parts of the cerebellum. For high school players, there was a significant difference for the parahippocampus and parts of the cerebellum. However, the only variable found to consistently predict the change in interhemispheric connectivity for these regions was the baseline interhemispheric connectivity. Future research will examine if there is a significant difference in the change in RCADS following a season of football to measure anxiety and depression in participants and if it predicts the change in interhemispheric connectivity.
subject
brain connectivity
concussion
fmri
head impacts
subconcussive
youth football
contributor
Kuhn, Tristan (author)
Whitlow, Christopher T (committee chair)
Urban, Jillian E. (committee member)
Bourland, John D. (committee member)
Whitlow, Christopher T. (committee member)
date
2020-08-28T08:35:22Z (accessioned)
2020 (issued)
degree
Biomedical Engineering (discipline)
2025-09-04 (liftdate)
embargo
2025-09-04 (terms)
identifier
http://hdl.handle.net/10339/96940 (uri)
language
en (iso)
publisher
Wake Forest University
title
THE EFFECT OF SUBCONCUSSIVE IMPACTS ON THE INTERHEMISPHERIC CONNECTIVITY OF BRAIN REGIONS IMPLICATED IN DEPRESSION AND ANXIETY OF HIGH SCHOOL AND YOUTH FOOTBALL PLAYERS AFTER ONE FULL SEASON OF PLAY
type
Thesis

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