Effects of Chronic Binge-like Ethanol Drinking on Early Cocaine Sensitivity in Rhesus Monkeys
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Item Details
- title
- Effects of Chronic Binge-like Ethanol Drinking on Early Cocaine Sensitivity in Rhesus Monkeys
- author
- Tryhus, Aaron
- abstract
- Aim: Most cocaine users also abuse alcohol, but little is known about the interaction between the two. These studies in rhesus monkeys compared the acquisition of cocaine self-administration in monkeys with or without a history of chronic, binge-like alcohol drinking. Raclopride PET imaging and quinpirole-induced yawning were conducted prior to drug exposure to look at the role of dopamine D2-like and D3 receptor availability, respectively, on initial acquisition.
- subject
- Alcohol
- Co-abuse
- Cocaine
- Dopamine
- Self-administration
- contributor
- Czoty, Paul W (committee chair)
- Weiner, Jeffrey L (committee member)
- Nader, Michael A (committee member)
- date
- 2020-08-28T08:35:29Z (accessioned)
- 2020-08-28T08:35:29Z (available)
- 2020 (issued)
- degree
- Biomedical Science – MS (discipline)
- identifier
- http://hdl.handle.net/10339/96955 (uri)
- language
- en (iso)
- publisher
- Wake Forest University
- type
- Thesis