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EXAMINING THE ASSOCIATION BETWEEN BODY COMPOSITION AND PHYSICAL FUNCTION IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE

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abstract
BACKGROUND: Current literature has yielded unequivocal results regarding the effect of obesity on physical function in patients with chronic obstructive pulmonary disease (COPD), a discrepancy that may be related to differences in defining and measuring obesity. The purpose of this study was to examine whether specific body composition measures were associated with physical function in COPD patients. METHODS: 170 COPD patients with complete dual-energy X-ray absorptiometry, six-minute walk (6MW), stair climb time (SCT), and self-report physical function questionnaire (PFQ) data were used for these analyses. Pearson product moment correlations were used to determine which measures of body composition were significantly correlated with physical function measures. Hierarchical multiple regression analysis was then used to determine if body composition measures correlated with physical function explained additional variance in physical function measures after controlling for body mass index (BMI) and disease severity. RESULTS: After accounting for BMI and disease severity, appendicular lean mass explained an additional 13.3% of variance in 6MWD and an additional 3.9% of variance in PFQ. Appendicular fat mass accounted for an additional 5.4% of variance in SCT. CONCLUSIONS: These results highlight the contribution of specific body composition measures in the performance of physical function tasks within the COPD population.
subject
body composition
chronic obstructive pulmonary disease
obesity
physical function
six-minute walk
contributor
Todoroff, Christa Marie (author)
Berry, Michael J (committee chair)
Brubaker, Peter (committee member)
Miller, Gary (committee member)
date
2021-06-03T08:36:20Z (accessioned)
2021 (issued)
degree
Health and Exercise Science (discipline)
2026-06-01 (liftdate)
embargo
2026-06-01 (terms)
identifier
http://hdl.handle.net/10339/98840 (uri)
language
en (iso)
publisher
Wake Forest University
title
EXAMINING THE ASSOCIATION BETWEEN BODY COMPOSITION AND PHYSICAL FUNCTION IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE
type
Thesis

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