MATRIX METALLOPROTEINASES AND LEFT VENTRICLE MASS AND FUNCTION

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dc.contributor.authorRana, Hamzaen_US
dc.date.accessioned2012-09-05T08:35:21Z
dc.date.available2014-09-05T08:30:08Z
dc.date.issued2012en_US
dc.description.abstractIntroduction: Left Ventricle (LV) remodelling is critical pathophysiological process in the development of heart failure. Previous published studies have suggested the pivotal role of matrix metalloproteinases and NT- pro BNP in the pathogenesis of LV remodelling. Our objective was to establish a biomarker of cardiac extra cellular matrix (ECM) degradation that can be used to better identify asymptomatic individuals with increased LV mass, impaired LV volumes and functions and those at risk for progression to clinical heart failure.en_US
dc.identifier.urihttps://wakespace.lib.wfu.edu/handle/10339/37444
dc.language.isoenen_US
dc.publisherWake Forest Universityen_US
dc.subjectcardiac MRIen_US
dc.subjectLV functionen_US
dc.subjectLV massen_US
dc.subjectMatrix metalloproteinaseen_US
dc.subjectNT-pro BNPen_US
dc.titleMATRIX METALLOPROTEINASES AND LEFT VENTRICLE MASS AND FUNCTIONen_US
dc.typeThesisen_US
thesis.contributor.committeeChairBurke, Gregory Len_US
thesis.contributor.committeeMemberCarr, John Jen_US
thesis.contributor.committeeMemberChen, Haiyingen_US
thesis.degree.disciplineClinical and Population Translational Sciencesen_US
thesis.embargo.terms2014-09-05en_US

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