DEVELOPMENT AND APPLICATION OF A MODULAR ENZYMATIC LABELING PROCESS FOR THE ANALYSIS OF DIVERSE DNA BASE MODIFICATIONS

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dc.contributor.authorWang, Fannyen_US
dc.date.accessioned2021-01-13T09:35:28Z
dc.date.available2021-01-13T09:35:28Z
dc.date.issued2021en_US
dc.description.abstractThere exists a large diversity of DNA base modifications, but the ability to study these modifications and their effects on disease development and progression has thus far been limited. Most techniques are only able to examine a few specific modifications, and some methods are destructive to the sample, precluding the possibility of additional analysis.en_US
dc.identifier.urihttps://wakespace.lib.wfu.edu/handle/10339/97957
dc.language.isoenen_US
dc.publisherWake Forest Universityen_US
dc.subjectDNA base modificationsen_US
dc.subjectglycosylaseen_US
dc.subjectlabelingen_US
dc.subjectnanoporeen_US
dc.subjectoxidative damageen_US
dc.subjectqPCRen_US
dc.titleDEVELOPMENT AND APPLICATION OF A MODULAR ENZYMATIC LABELING PROCESS FOR THE ANALYSIS OF DIVERSE DNA BASE MODIFICATIONSen_US
dc.typeDissertationen_US
thesis.contributor.committeeChairHall, Adam Ren_US
thesis.contributor.committeeMemberFurdui, Cristina Men_US
thesis.contributor.committeeMemberKohli, Rahul Men_US
thesis.contributor.committeeMemberLu, Changen_US
thesis.contributor.committeeMemberPerrino, Fred Wen_US
thesis.contributor.committeeMemberRahbar, Elahehen_US
thesis.degree.disciplineBiomedical Engineeringen_US

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