2026-09-20T11:16:42Zhttps://wakespace.lib.wfu.edu/server/oai/request

oai:null:10339/303922026-09-02T08:27:21Zcom_10339_14934col_10339_38132

Brzoza-Lewis, Kristina Lynn 2011-02-16T21:42:12Z 2011-03-30T14:04:37Z 2010 https://wakespace.lib.wfu.edu/handle/10339/30392 <italic>Listeria monocytogenes (Lm)</italic> is an intracellular bacterial pathogen that is of consequence to pregnant women and immunocompromised individuals. Exploiting a niche, <italic>Lm</italic> gains access to the host cell cytosol via the pore forming toxin listeriolysin O (LLO) and infects a variety of cell types including dendritic cells (DC). Our laboratory and others have shown that optimal DC maturation occurs when <italic>Listeria</italic> gain access to the host cytosol, and this correlates with protective immunity. en Wake Forest University Dendritic cell Innate immunity Listeria monocytogenes Neutrophil Type I IFN response Innate Immunity to Listeria monocytogenes Infection: Regulation of Dendritic Cell and Neutrophil Responses by MyD88 and the Type I IFN Receptor Dissertation Schwartz, Elizabeth H Fetrow, Jacquelyn S Alexander-Miller, Martha A Grayson, Jason M McPhail, Linda C Molecular Genetics & Genomics 2011-02-17 open.access