<?xml version="1.0" encoding="UTF-8"?><?xml-stylesheet type="text/xsl" href="static/style.xsl"?><OAI-PMH xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd"><responseDate>2026-09-23T05:44:03Z</responseDate><request verb="GetRecord" identifier="oai:wakespace.lib.wfu.edu:10339/30414" metadataPrefix="dim">https://wakespace.lib.wfu.edu/server/oai/request</request><GetRecord><record><header><identifier>oai:null:10339/30414</identifier><datestamp>2026-09-02T10:53:55Z</datestamp><setSpec>com_10339_14934</setSpec><setSpec>col_10339_38132</setSpec></header><metadata><dim:dim xmlns:dim="http://www.dspace.org/xmlns/dspace/dim" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:doc="http://www.lyncode.com/xoai" xsi:schemaLocation="http://www.dspace.org/xmlns/dspace/dim http://www.dspace.org/schema/dim.xsd">
   <dim:field mdschema="dc" element="contributor" qualifier="author" lang="en_US">Rong, Shunxing</dim:field>
   <dim:field mdschema="dc" element="date" qualifier="accessioned">2011-02-16T21:42:28Z</dim:field>
   <dim:field mdschema="dc" element="date" qualifier="available">2011-06-10T08:30:11Z</dim:field>
   <dim:field mdschema="dc" element="date" qualifier="issued" lang="en_US">2010</dim:field>
   <dim:field mdschema="dc" element="identifier" qualifier="uri">https://wakespace.lib.wfu.edu/handle/10339/30414</dim:field>
   <dim:field mdschema="dc" element="description" qualifier="abstract" lang="en_US">12/15 lipoxygenase (LO) is a member of a family of enzymes that can catalyze the stereospecific incorporation of oxygen into polyunsaturated fatty acids (PUFAs), forming a series of bioactive lipid mediators. Though lipid mediators produced by 12/15LO have the potential to affect lipid metabolism and atherosclerosis, the role of 12/15LO expression in these processes has not been elucidated.</dim:field>
   <dim:field mdschema="dc" element="language" qualifier="iso" lang="en_US">en</dim:field>
   <dim:field mdschema="dc" element="publisher" lang="en_US">Wake Forest University</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">Atherosclerosis</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">Lipid metabolism</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">Lipoxygenase</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">Macrophage</dim:field>
   <dim:field mdschema="dc" element="title" lang="en_US">ROLE OF 12/15 LIPOXYGENASE EXPRESSION IN LIPID METABOLISM, ATHEROSCLEROSIS AND INSULIN RESISTANCE</dim:field>
   <dim:field mdschema="dc" element="type" lang="en_US">Dissertation</dim:field>
   <dim:field mdschema="thesis" element="contributor" qualifier="committeeChair" lang="en_US">Parks, John S.</dim:field>
   <dim:field mdschema="thesis" element="contributor" qualifier="committeeMember" lang="en_US">Rudel, Lawrence L.</dim:field>
   <dim:field mdschema="thesis" element="contributor" qualifier="committeeMember" lang="en_US">Temel, Ryan E.</dim:field>
   <dim:field mdschema="thesis" element="contributor" qualifier="committeeMember" lang="en_US">Shelness, Gregory S.</dim:field>
   <dim:field mdschema="thesis" element="degree" qualifier="discipline" lang="en_US">Molecular Pathology</dim:field>
   <dim:field mdschema="thesis" element="embargo" qualifier="terms" lang="en_US">2011-06-10</dim:field>
   <dim:field mdschema="others" element="access-status">open.access</dim:field>
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