<?xml version="1.0" encoding="UTF-8"?><?xml-stylesheet type="text/xsl" href="static/style.xsl"?><OAI-PMH xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd"><responseDate>2026-09-19T21:51:29Z</responseDate><request verb="GetRecord" identifier="oai:wakespace.lib.wfu.edu:10339/36157" metadataPrefix="dim">https://wakespace.lib.wfu.edu/server/oai/request</request><GetRecord><record><header><identifier>oai:null:10339/36157</identifier><datestamp>2026-09-02T13:16:10Z</datestamp><setSpec>com_10339_14934</setSpec><setSpec>col_10339_38132</setSpec></header><metadata><dim:dim xmlns:dim="http://www.dspace.org/xmlns/dspace/dim" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:doc="http://www.lyncode.com/xoai" xsi:schemaLocation="http://www.dspace.org/xmlns/dspace/dim http://www.dspace.org/schema/dim.xsd">
   <dim:field mdschema="dc" element="contributor" qualifier="author" lang="en_US">Jessup, Jewell</dim:field>
   <dim:field mdschema="dc" element="date" qualifier="accessioned">2011-09-08T08:36:01Z</dim:field>
   <dim:field mdschema="dc" element="date" qualifier="available">2011-09-08T08:36:01Z</dim:field>
   <dim:field mdschema="dc" element="date" qualifier="issued" lang="en_US">2011</dim:field>
   <dim:field mdschema="dc" element="identifier" qualifier="uri">https://wakespace.lib.wfu.edu/handle/10339/36157</dim:field>
   <dim:field mdschema="dc" element="description" qualifier="abstract" lang="en_US">It is increasingly recognized that biological differences in the mechanisms regulating cardiovascular function in women and men critically impact the expression, clinical presentation, and outcomes of chronic diseases such as hypertension, diabetes, and heart failure.  This is borne out from epidemiological and clinical studies that have explored the prevalence and presentation of heart disease in women, as well as a robust experimental literature demonstrating a role of estrogens in cardioprotection.  Sex differences in mortality after myocardial infarction tell the story since data show a worse prognosis of death post-myocardial infarction for women (38% within the first year) compared to men (25% within the first year).</dim:field>
   <dim:field mdschema="dc" element="language" qualifier="iso" lang="en_US">en</dim:field>
   <dim:field mdschema="dc" element="publisher" lang="en_US">Wake Forest University</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">BH4</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">Collagen</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">Diastolic Function</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">Estrogens</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">Nitric Oxide</dim:field>
   <dim:field mdschema="dc" element="title" lang="en_US">THE INTERPLAY BETWEEN ESTROGENS AND THE NITRIC OXIDE SYSTEM IN CARDIAC FUNCTION AND STRUCTURE</dim:field>
   <dim:field mdschema="dc" element="type" lang="en_US">Dissertation</dim:field>
   <dim:field mdschema="thesis" element="contributor" qualifier="committeeChair" lang="en_US">Groban, Leanne</dim:field>
   <dim:field mdschema="thesis" element="contributor" qualifier="committeeMember" lang="en_US">Robbins, Michael E.C.</dim:field>
   <dim:field mdschema="thesis" element="contributor" qualifier="committeeMember" lang="en_US">Shively, Carol A.</dim:field>
   <dim:field mdschema="thesis" element="contributor" qualifier="committeeMember" lang="en_US">Sane, David C.</dim:field>
   <dim:field mdschema="thesis" element="contributor" qualifier="committeeMember" lang="en_US">Chappell, Mark</dim:field>
   <dim:field mdschema="thesis" element="degree" qualifier="discipline" lang="en_US">Physiology and Pharmacology</dim:field>
   <dim:field mdschema="others" element="access-status">open.access</dim:field>
</dim:dim>
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