2026-09-21T11:46:54Zhttps://wakespace.lib.wfu.edu/server/oai/request

oai:null:10339/374432026-09-02T16:21:29Zcom_10339_14934col_10339_38132

Best, Ryan C. M. 2012-09-05T08:35:21Z 2013-03-05T09:30:05Z 2012 https://wakespace.lib.wfu.edu/handle/10339/37443 The Gamma Knife Perfexion is a radiosurgical treatment device used to irradiate targets in the head. It uses 192 high-activity Cobalt-60 sources collimated to a common focus to impart radiological damage to the target structure while minimizing dose to adjacent healthy tissue. Tungsten collimators are organized into eight sectors of 24 sources each; each sector can be set to one of three collimation sizes. The collimators can produce nominal spheres of dose 16 mm, 8 mm, or 4 mm in diameter at the focus. Planning for Gamma Knife stereotactic radiosurgery (GK SRS) is performed using images from computed tomography (CT) and/or magnetic resonance (MR) imaging, as well as manual skull measurements. The manufacturer's software used to plan the delivery of these treatments uses a simplistic set of assumptions that do not consider heterogeneous tissue structures. en Wake Forest University dose distribution independent check Maximum Allowed Dose Difference radiosurgery stereotactic verification A Complete Dosimetric Model of the Gamma Knife Perfexion Using Penelope Monte Carlo Codes Dissertation Bourland, J. Daniel Hinson, William H Holzwarth, George Salsbury, Jr., Fred R Munley, Michael T Physics 2013-03-05 open.access