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oai:null:10339/374442026-09-02T08:21:09Zcom_10339_14934col_10339_38132

Rana, Hamza 2012-09-05T08:35:21Z 2014-09-05T08:30:08Z 2012 https://wakespace.lib.wfu.edu/handle/10339/37444 Introduction: Left Ventricle (LV) remodelling is critical pathophysiological process in the development of heart failure. Previous published studies have suggested the pivotal role of matrix metalloproteinases and NT- pro BNP in the pathogenesis of LV remodelling. Our objective was to establish a biomarker of cardiac extra cellular matrix (ECM) degradation that can be used to better identify asymptomatic individuals with increased LV mass, impaired LV volumes and functions and those at risk for progression to clinical heart failure. en Wake Forest University cardiac MRI LV function LV mass Matrix metalloproteinase NT-pro BNP MATRIX METALLOPROTEINASES AND LEFT VENTRICLE MASS AND FUNCTION Thesis Burke, Gregory L Carr, John J Chen, Haiying Clinical and Population Translational Sciences 2014-09-05 restricted