2026-09-25T21:32:15Zhttps://wakespace.lib.wfu.edu/server/oai/request

oai:null:10339/392872026-09-02T13:50:08Zcom_10339_14934col_10339_38132

Stovall, Daniel B. 2014-07-10T08:35:34Z 2014-07-10T08:35:34Z 2014 https://wakespace.lib.wfu.edu/handle/10339/39287 Second only to lung cancer, breast cancer is the leading cause of cancer-related deaths in American women. Breast cancer is a heterogeneous set of diseases characterized by aberrant genetic and epigenetic states, often leading to the ablation of tumor suppressors. Loss of tumor suppressor function has been established as a driver of disease progression in breast cancer patients. Thus, understanding the deregulation of tumor suppressor activity may lead to the identification of potential therapeutic targets whose inhibition can restore tumor suppressor function and, consequently, an anti-proliferative cellular state. en Wake Forest University breast cancer epigenetics noncoding RNA SOX7 tumor suppressor SOX7 is downregulated and functions as a tumor suppressive transcription factor in breast cancer Dissertation Sui, Guangchao Wang, Yuh-Hwa Seals, Darren F Pardee, Timothy S Wadas, Thaddeus Cancer Biology open.access