2026-09-20T12:23:48Zhttps://wakespace.lib.wfu.edu/server/oai/request

oai:null:10339/393302026-09-18T13:44:11Zcom_10339_14934col_10339_38132

Schaich, Chris 2014-07-10T08:35:43Z 2014-07-10T08:35:43Z 2014 https://wakespace.lib.wfu.edu/handle/10339/39330 Hypertension is associated with various conditions including obesity, type II diabetes and aging. Despite decades of research, the mechanisms involved in the development of hypertension are still poorly understood. Emerging evidence suggests hypertension is mediated by an imbalance in autonomic nervous system activity. Baroreflex sensitivity for control of heart rate, an important index of vagus nerve function as well as general morbidity and mortality, is often impaired in conditions associated with hypertension. Restoration of baroreflex function is now recognized as a therapeutic strategy for prevention of cardiovascular diseases. Therefore, it is crucial to identify key factors that regulate brainstem regions controlling autonomic outflow in conditions associated with baroreflex dysfunction. en Wake Forest University Autonomic Nervous System Baroreflex Endocannabinoid System Hypertension Renin-Angiotensin System Blood Pressure Regulation by the Endocannabinoid System in Conditions Associated with Hypertension Dissertation Diz, Debra I Howlett, Allyn C Pratt, Wayne E Shaltout, Hossam A Thomas, Brian F Physiology and Pharmacology open.access