2026-09-21T14:37:42Zhttps://wakespace.lib.wfu.edu/server/oai/request

oai:null:10339/474582026-09-02T12:24:08Zcom_10339_14934col_10339_38132

Jordan, Jennifer Hawthorne 2015-01-21T09:35:18Z 2014 https://wakespace.lib.wfu.edu/handle/10339/47458 In this thesis, we will evaluate the effect of anthracycline chemotherapy on measures of myocardial injury and fibrosis using quantitative cardiovascular magnetic resonance (CMR) imaging techniques. Anthracycline-based chemotherapy regimens are often an essential component of curative cancer treatments, but are associated with myocardial injury, heart failure, and cardiovascular events. Elevated native T1 and extracellular volume (ECV) assessments indicative of myocardial fibrosis or injury have been observed in adult cancer survivors treated with anthracyclines. It remains undetermined, however, whether these measures are related to the cancer or the treatment for cancer. en Wake Forest University Cardiotoxicity Cardiovascular Magnetic Resonance Imaging Extracellular Volume Myocardial Fibrosis Myocardial T1 Assessment of Myocardial Fibrosis using Cardiovascular Magnetic Resonance Extracellular Volume Mapping in Cancer Patients Treated with Anthracycline-based Chemotherapy Compared with Untreated Cancer Patients and Cancer-free Peers Thesis Hundley, William G Burke, Gregory L Hamilton, Craig A Morgan, Timothy M Clinical and Population Translational Sciences forever 10000-01-01 open.access