2026-09-21T00:11:24Zhttps://wakespace.lib.wfu.edu/server/oai/request

oai:null:10339/571032026-09-18T12:52:39Zcom_10339_14934col_10339_38132

Kromrey, Sarah Allyson 2015-06-23T08:35:36Z 2017-06-22T08:30:10Z 2015 https://wakespace.lib.wfu.edu/handle/10339/57103 There are currently no FDA-approved drug treatments for cocaine abuse. The use of female subjects and a better understanding of the influence of hormones and cognitive function may provide valuable information to aid in pharmacotherapy development. The present studies utilized female monkeys housed in groups of four to examine the interactions of social rank and hormone concentrations on vulnerability to cocaine reinforcement and cognitive function. The overarching goal was to characterize how estradiol (E2) and progesterone (P4) concentrations influence cognitive performance, eventual social rank and vulnerability to cocaine self-administration (SA). We also examined how social rank altered these and additional hormonal measures. en Wake Forest University cocaine cognition estradiol monkey social rank Endogenous hormonal milieu of female cynomolgus monkeys: interaction with cognitive performance, social rank and acquisition of cocaine self-administration Dissertation Nader, Michael Voytko, MaryLou Appt, Susan Kaplan, Jay Neuroscience 2017-06-22 open.access