<?xml version="1.0" encoding="UTF-8"?><?xml-stylesheet type="text/xsl" href="static/style.xsl"?><OAI-PMH xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd"><responseDate>2026-09-20T08:37:50Z</responseDate><request verb="GetRecord" identifier="oai:wakespace.lib.wfu.edu:10339/57120" metadataPrefix="dim">https://wakespace.lib.wfu.edu/server/oai/request</request><GetRecord><record><header><identifier>oai:null:10339/57120</identifier><datestamp>2026-09-16T09:03:20Z</datestamp><setSpec>com_10339_14934</setSpec><setSpec>col_10339_38132</setSpec></header><metadata><dim:dim xmlns:dim="http://www.dspace.org/xmlns/dspace/dim" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:doc="http://www.lyncode.com/xoai" xsi:schemaLocation="http://www.dspace.org/xmlns/dspace/dim http://www.dspace.org/schema/dim.xsd">
   <dim:field mdschema="dc" element="contributor" qualifier="author" lang="en_US">Guo, Xinyi</dim:field>
   <dim:field mdschema="dc" element="date" qualifier="accessioned">2015-06-23T08:35:43Z</dim:field>
   <dim:field mdschema="dc" element="date" qualifier="available">2015-06-23T08:35:43Z</dim:field>
   <dim:field mdschema="dc" element="date" qualifier="issued" lang="en_US">2015</dim:field>
   <dim:field mdschema="dc" element="identifier" qualifier="uri">https://wakespace.lib.wfu.edu/handle/10339/57120</dim:field>
   <dim:field mdschema="dc" element="description" qualifier="abstract" lang="en_US">Tissue engineering strategies nowadays require attention to not only cells, but also to the mechanical properties of the extracellular matrix (ECM).We studied the elasticity of hydrogels formulations frequently used in cell and tissue culturing. A variety of concentrations in a variety of biomaterials, including agarose, alginate, the collagens, fibrin, hyaluronic acid, kerateine, laminin, Matrigel, and polyethylene glycol diacrylate (PEGDA), were tested with atomic force microscopy (AFM). We also determined the Young’s modulus (E) of hydrogels with different concentrations.  E tended to increase with increased concentration.</dim:field>
   <dim:field mdschema="dc" element="language" qualifier="iso" lang="en_US">en</dim:field>
   <dim:field mdschema="dc" element="publisher" lang="en_US">Wake Forest University</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">Atomic Force Microscopy</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">Breast Cancer</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">Cancer cells</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">Hydrogels</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">Multiple Myeloma</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">Young&amp;apos;s Modulus</dim:field>
   <dim:field mdschema="dc" element="title" lang="en_US">CHARACTERIZING THE MICRO-SCALE MECHANICAL PROPERTIES OF HYDROGELS   AND CANCER CELLS</dim:field>
   <dim:field mdschema="dc" element="type" lang="en_US">Dissertation</dim:field>
   <dim:field mdschema="thesis" element="contributor" qualifier="committeeChair" lang="en_US">Guthold, Martin</dim:field>
   <dim:field mdschema="thesis" element="contributor" qualifier="committeeMember" lang="en_US">Bierbach, Ulrich</dim:field>
   <dim:field mdschema="thesis" element="contributor" qualifier="committeeMember" lang="en_US">Holzwarth, George</dim:field>
   <dim:field mdschema="thesis" element="contributor" qualifier="committeeMember" lang="en_US">Macosko, Jed</dim:field>
   <dim:field mdschema="thesis" element="contributor" qualifier="committeeMember" lang="en_US">Guthold, Martin</dim:field>
   <dim:field mdschema="thesis" element="degree" qualifier="discipline" lang="en_US">Physics</dim:field>
   <dim:field mdschema="others" element="access-status">open.access</dim:field>
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