2026-09-19T22:16:12Zhttps://wakespace.lib.wfu.edu/server/oai/request

oai:null:10339/571572026-09-18T12:44:41Zcom_10339_14934col_10339_38132

Johnson, Steven Michael 2015-06-23T08:35:54Z 2015-06-23T08:35:54Z 2015 https://wakespace.lib.wfu.edu/handle/10339/57157 Post-translational modifications (PTMs) are an important step in the formation of a mature protein. While much is known about some PTMs such as Phosphorylation, there are other PTMs such as Cysteine S-sulfenylation that are currently being researched and analyzed. For this project, an algorithm, Bit-Motif, was developed to analyze modification sites of PTMs by discovering statistically significant motifs around these sites. These motifs were then used as features for a Support Vector Machine to build a prediction model for PTM sites, called Prediction Using Motifs for PTMs (PUMP). en Wake Forest University Motif Search Post-Translational Modification Support Vector Machine Algorithms to Detect Motifs and Predict Post-Translational Modification Sites Thesis Turkett, William H Cho, Samuel Poole, Leslie Computer Science open.access