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Baker, Stephen Robert 2015-08-25T08:35:35Z 2016-02-24T09:30:09Z 2015 https://wakespace.lib.wfu.edu/handle/10339/57263 The extracellular matrix is comprised mostly of collagen, the most abundant protein in the body. This protein helps to provide the structural support for various tissues such as skin, muscles, tendons, and even heart valves and blood vessels. Fibrinogen is the most abundant protein found in blood plasma. After exposure to thrombin, it is converted to fibrin, and provides the structural support of a blood clot. These natural polymers, along with synthetic polymers, can be synthesized outside the body by a process known as electrospinning. Electrospinning can be used to make nanofibers which form the macrostructure scaffold to be tailored to specific applications. The mechanical properties en Wake Forest University Atomic Force Microscopy Electrospinning Fibrin Nanomechanics Single Fiber Determining Single Fiber Nanomechanical Properties of Electrospun Protein Fibers and Modified Fibrin Fibers Using Atomic Force Microscopy Dissertation Guthold, Martin Hall, Adam Bonin, Keith Holzwarth, George Kim-Shapiro, Daniel Physics 2016-02-24 open.access