2026-09-19T13:07:36Zhttps://wakespace.lib.wfu.edu/server/oai/request

oai:null:10339/592602026-09-18T10:40:33Zcom_10339_14934col_10339_38132

Martelle, Susan Elizabeth 2016-05-21T08:35:27Z 2016-11-20T09:30:12Z 2016 https://wakespace.lib.wfu.edu/handle/10339/59260 Dopamine is the most common neurotransmitter in the mammalian brain and is a key modulator of reward-related behaviors. Through the use of animal models, the dopaminergic system has been implicated in several neuropsychiatric disorders. Furthermore, the application of genetic technologies has helped uncover how modulation of dopaminergic signaling leads to modification of normal behavior and contributes to negative phenotypes and symptoms associated with diseases like attention-deficit/hyperactivity disorder, cocaine dependence, and obesity. This dissertation explores a number of behaviors, learned and unconditioned, and the contribution of dopaminergic neurotransmission to each by using both human and non-human primates as subjects. en Wake Forest University Cognition dopa decarboxylase Dopamine Dopamine D3 receptors Type 2 diabetes yawning A study of the neuropharmacology and genetics of dopamine: using common, preclinical behavioral techniques, cognitive batteries, and genetic analyses to unravel the dopaminergic system Dissertation Bowden, Donald W Allred, Nicholette D Howard, Timothy Jorgensen, Matthew J Weiner, Jeffrey Physiology and Pharmacology 2016-11-20 open.access