2026-09-20T21:15:32Zhttps://wakespace.lib.wfu.edu/server/oai/request

oai:null:10339/626462026-09-18T14:10:34Zcom_10339_14934col_10339_38132

Blevins, Lance Kendall 2016-08-25T08:35:23Z 2018-08-19T08:30:09Z 2016 https://wakespace.lib.wfu.edu/handle/10339/62646 Infection with influenza A virus (IAV) can lead to increased susceptibility to subsequent bacterial infection, often with Streptococcus pneumoniae (Spn). Clinical and experimental data indicate increased disease severity when a coinfecting agent is present during IAV infection, indicating the need to understand how the presence of a coinfecting pathogen can modulate the ongoing adaptive CD8+ T cell response to IAV. en Wake Forest University Coinfection Immune regulation Influenza pneumococcus Streptococcus pneumoniae mediated negative regulation of CD8+ T cell effector function Dissertation Alexander-Miller, Martha A Lyles, Douglas S Haas, Karen M Grayson, Jason M Swords, William E Parsonage, Derek Microbiology & Immunology 2018-08-19 open.access