2026-09-20T08:54:45Zhttps://wakespace.lib.wfu.edu/server/oai/request

oai:null:10339/821582026-09-02T09:44:32Zcom_10339_14934col_10339_38132

Braco, Jason Thomas 2017-06-15T08:35:27Z 2021-12-30T09:30:14Z 2017 https://wakespace.lib.wfu.edu/handle/10339/82158 The mechanisms of how organisms maintain metabolic homeostasis in light of significant environmental variation in food availability are not completely understood. In Drosophila, the mobilization of energy is primarily controlled by the endocrine factor Adipokinetic Hormone (AKH). AKH function is critical for proper energy allocation under ad libitum conditions, and is particularly important for the physiological and behavioral response to metabolic stress. Animals lacking AKH display multiple stress phenotypes including increased lifespan under starvation and the absence of starvation-induced locomotion. Research has primarily focused on understanding the downstream targets of AKH action, however, little work has explored AKH cell physiology and the mechanisms that govern AKH release. en Wake Forest University AKH Drosophila Metabolism Starvation FUNCTIONAL DISSECTION OF ADIPOKINETIC HORMONE PRODUCING CELLS Dissertation Johnson, Erik C Marrs, Glen S Silver, Wayne L Zeyl, Clifford W Biology 2021-12-30 open.access