<?xml version="1.0" encoding="UTF-8"?><?xml-stylesheet type="text/xsl" href="static/style.xsl"?><OAI-PMH xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd"><responseDate>2026-09-21T07:13:57Z</responseDate><request verb="GetRecord" identifier="oai:wakespace.lib.wfu.edu:10339/82159" metadataPrefix="dim">https://wakespace.lib.wfu.edu/server/oai/request</request><GetRecord><record><header><identifier>oai:null:10339/82159</identifier><datestamp>2026-09-02T15:07:33Z</datestamp><setSpec>com_10339_14934</setSpec><setSpec>col_10339_38132</setSpec></header><metadata><dim:dim xmlns:dim="http://www.dspace.org/xmlns/dspace/dim" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:doc="http://www.lyncode.com/xoai" xsi:schemaLocation="http://www.dspace.org/xmlns/dspace/dim http://www.dspace.org/schema/dim.xsd">
   <dim:field mdschema="dc" element="contributor" qualifier="author" lang="en_US">Okoukoni, Catherine</dim:field>
   <dim:field mdschema="dc" element="date" qualifier="accessioned">2017-06-15T08:35:29Z</dim:field>
   <dim:field mdschema="dc" element="date" qualifier="available">2019-06-14T08:30:12Z</dim:field>
   <dim:field mdschema="dc" element="date" qualifier="issued" lang="en_US">2017</dim:field>
   <dim:field mdschema="dc" element="identifier" qualifier="uri">https://wakespace.lib.wfu.edu/handle/10339/82159</dim:field>
   <dim:field mdschema="dc" element="description" qualifier="abstract" lang="en_US">Bone fracture is a major complication of radiation therapy (RT). The etiology of RT-induced fractures is unclear, but likely involves bone damage and deterioration. Unfortunately, there remains a paucity of quantitative data on structural bone changes after exposure to RT. The primary goal of this project is to quantify RT-related structural bone changes in cancer patients using computed tomography (CT) scans obtained in the course of treatment.  Our hypothesis is that exposure to radiation produces early structural changes in the cortical and trabecular bone compartments.</dim:field>
   <dim:field mdschema="dc" element="language" qualifier="iso" lang="en_US">en</dim:field>
   <dim:field mdschema="dc" element="publisher" lang="en_US">Wake Forest University</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">Bone</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">Computed Tomography</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">Radiation</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">Toxicity</dim:field>
   <dim:field mdschema="dc" element="title" lang="en_US">QUANTIFYING RADIATION INDUCED CORTICAL BONE LOSS USING COMPUTED TOMOGRAPHY (CT) IMAGING</dim:field>
   <dim:field mdschema="dc" element="type" lang="en_US">Dissertation</dim:field>
   <dim:field mdschema="thesis" element="contributor" qualifier="committeeChair" lang="en_US">Munley, Michael T</dim:field>
   <dim:field mdschema="thesis" element="contributor" qualifier="committeeMember" lang="en_US">Willey, Jeffery S</dim:field>
   <dim:field mdschema="thesis" element="contributor" qualifier="committeeMember" lang="en_US">Blackstock, A. William</dim:field>
   <dim:field mdschema="thesis" element="contributor" qualifier="committeeMember" lang="en_US">Weaver, Ashley A</dim:field>
   <dim:field mdschema="thesis" element="contributor" qualifier="committeeMember" lang="en_US">Bourland, J.Daniel</dim:field>
   <dim:field mdschema="thesis" element="degree" qualifier="discipline" lang="en_US">Biomedical Engineering</dim:field>
   <dim:field mdschema="thesis" element="embargo" qualifier="terms" lang="en_US">2019-06-14</dim:field>
   <dim:field mdschema="others" element="access-status">open.access</dim:field>
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