2026-09-23T20:59:02Zhttps://wakespace.lib.wfu.edu/server/oai/requestoai:null:10339/923872026-09-18T12:12:51Zcom_10339_14934col_10339_38132
Ghiraldeli, Lais Pereira
2018-08-23T08:35:40Z
2020-08-22T08:30:14Z
2018
https://wakespace.lib.wfu.edu/handle/10339/92387
Acute myeloid leukemia (AML) is an aggressive cancer of the bone marrow characterized by poor prognosis and resistance to chemotherapy. The way in which cancerous cells are able to metabolically adapt to various physiological and metabolic stressors allows them to thrive and proliferate. A leading candidate to coordinate this oxidative metabolic shift is the AMP-activated protein kinase (AMPK).
en
Wake Forest University
AML
AMPK
Chemotherapy
Chemotherapy Resistance
Resistance
AMP-ACTIVATED PROTEIN KINASE AND ITS ROLE IN THERAPEUTIC RESPONSE IN ACUTE MYELOID LEUKEMIA
Thesis
Pardee, Timothy
Kerr, Bethany
Smith, Thomas
Cancer Biology
2020-08-22
open.access