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Fibroblast Growth Factor-23 and Cardiac Magnetic Resonance Indices of Myocardial Fibrosis in the Multi-Ethnic Study of Atherosclerosis

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abstract
In this thesis, we will evaluate the association of Fibroblast Growth Factor-23 (FGF-23) with myocardial fibrosis using cardiovascular magnetic resonance (CMR) imaging techniques. Higher levels of Fibroblast Growth Factor-23 (FGF-23) have been linked to increased risk of all-cause mortality, cardiovascular mortality, left ventricular hypertrophy and heart failure. Histologic studies on rats suggest an association between higher levels of FGF-23 with myocardial fibrosis. However, it is unknown whether such relationship exists in humans.
subject
CKD
CMR
FGF-23
heart failure
myocardial fibrosis
contributor
Almahmoud, Mohamed Faher (author)
Herrington, David M (committee chair)
Jordan, Jennifer Hawthorne (committee member)
Snively, Beverly M (committee member)
date
2016-05-21T08:35:54Z (accessioned)
2017-05-20T08:30:08Z (available)
2016 (issued)
degree
Clinical and Population Translational Sciences (discipline)
embargo
2017-05-20 (terms)
identifier
http://hdl.handle.net/10339/59329 (uri)
language
en (iso)
publisher
Wake Forest University
title
Fibroblast Growth Factor-23 and Cardiac Magnetic Resonance Indices of Myocardial Fibrosis in the Multi-Ethnic Study of Atherosclerosis
type
Thesis

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