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THE PHOTOISOMERIZATION OF 2-PHENYL-3H-INDOL-3-ONE N-OXIDE (2- PHENYLISATOGEN) TO 2-PHENYL-4H-3,1-BENZOXAZIN-4-ONE

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abstract
The use of nitrones is an important synthetic tool for the organic chemist. An unusual reaction of these nitrones is a photochemical ring expansion under proper conditions that allows the nitrone oxygen to migrate past a carbon atom in a ring and insert itself into a ring that is expanded by the oxygen. While the process occurs for a number of six-membered rings, there is only one known five member ring expansion which seems to offer a possible mechanism. This thesis discusses this mechanism and offers evidence that an isomeric oxaziridine ring created from the nitrone offers a possible explanation of the mechanism
subject
isomerization
organic
photochemistry
contributor
Squire, Richard Huffman (author)
Jones, Paul B. (committee chair)
Salem, Akbar (committee member)
Welker, Mark E (committee member)
date
2016-05-21T08:35:55Z (accessioned)
2016-05-21T08:35:55Z (available)
2016 (issued)
degree
Chemistry (discipline)
identifier
http://hdl.handle.net/10339/59333 (uri)
language
en (iso)
publisher
Wake Forest University
title
THE PHOTOISOMERIZATION OF 2-PHENYL-3H-INDOL-3-ONE N-OXIDE (2- PHENYLISATOGEN) TO 2-PHENYL-4H-3,1-BENZOXAZIN-4-ONE
type
Thesis

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